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PanoFlow

PanoFlow / High-throughput Brain Slice Analyzer

A Capable Assistant for Your Research

PanoFlow is a high-throughput brain slice analyzer built on PanoBrain, with higher throughput and a smoother research workflow experience

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High Throughput

260 slides

High Throughput

One instrument supports both fluorescence and brightfield imaging, with fast switching, high-resolution brightfield imaging, multi-channel fluorescence, and up to 7-channel fluorescence imaging

90 slides/h

High-speed Scanning

The high-throughput brain slice analyzer can scan 90 slices within a 15 × 15 mm² area using 20X brightfield scanning

Progress Alerts

Thoughtful Reminders

Large batch scanning can take time. The system automatically sends a message after scanning is complete, so you can track progress even when away from the instrument

Intuitive

Easy Operation

The interface is clean and intuitive. Users can become familiar with the workflow in just 5 minutes and start slide scanning smoothly

No Breakage Risk

Slide Holder Solution

Slides move synchronously with the slide holder, effectively avoiding breakage risks that may occur when pushing individual slides

One-click Atlas Registration

Multiple brain atlas types for diverse registration needs

Rat Brain Atlas

Rat Brain Atlas

Mouse Brain Atlas

Mouse Brain Atlas

Macaque Brain Atlas

Macaque Brain Atlas

Ferret Brain Atlas

Ferret Brain Atlas

One-click multi-slice registration for a major efficiency boost

One-click multi-slice registration for a major efficiency boost

Automated Fluorescence Quantitative Analysis

Cell Counting

Cell Counting

Supports automatic recognition of DAPI, c-Fos, neurons, glial cells, and other signals, and counts positive signal cells

Density Analysis

Density Analysis

Supports automatic recognition of DAPI, c-Fos, neurons, glial cells, and other signals, with statistics for positive signal area and fluorescence intensity

Batch Analysis

Batch Analysis

Supports batch analysis of multiple brain slices on the same slide, reducing repetitive manual work, improving analysis efficiency, and ensuring parameter consistency

Effortless Result Visualization

Rat Brain Atlas
Macaque Brain Atlas
Macaque Brain Atlas

Fully Loaded Highlights

Fluorescence and Brightfield Dual Mode

One instrument supports both fluorescence and brightfield imaging modes, with fast switching between the two

7-channel Fluorescence

Supports 7-channel fluorescence imaging with general channel configurations for common applications, plus customizable filters to reduce crosstalk concerns

Clear Imaging of Thick Samples

Z-Stack scanning and extended depth of field fuse images from different focal planes in real time, producing fully focused images with clear layered details. Clear images can also be selectively extracted from the image sequence and stacked, reducing multi-layer fusion blur caused by defocus

99% Uniformity

Uniform illumination and global fluorescence background correction achieve up to 99% fluorescence background uniformity for seamless panoramic images

Low Fluorescence Quenching

Strobe illumination provides millisecond-level high instantaneous power only during camera exposure, reducing fluorescence quenching. Scanned samples can still be used for confocal imaging

Custom Modules

Custom modules are available for multi-channel fluorescence, large slide holders, sCMOS cameras, and throughput expansion

More Throughput Options, Easier Fit

PanoFlow-60

Designed for daily batch scanning in medium-throughput laboratories, balancing efficiency and footprint

PanoFlow-120

For more frequent serial section tasks, helping teams steadily improve sample processing efficiency

PanoFlow-260

A higher-throughput configuration for large-scale brain slice scanning and long unattended acquisition sessions

PanoFlow-Custom

Custom modules are available for multi-channel fluorescence, large slide holders, sCMOS cameras, and throughput expansion

Bring PanoFlow Into Your Lab

Move high-throughput brain slice scanning, analysis, and result delivery into a steadier automated workflow

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