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PanoBrain

PanoBrain / Fully Automatic Brain Slice Analyzer

Simplify Neuroscience Workflows

PanoBrain rapidly scans brain slices to capture high-resolution digital panoramic images, then automatically performs quantitative analysis such as brain-region segmentation, atlas registration, and cell counting. It automates the full workflow from imaging to data processing and reshapes neuroscience research workflows

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One-click Atlas Registration

One-click Atlas Registration

One-click registration

Automatically identifies brain slices and matches them to the Allen Brain Atlas

Cell Recognition and Counting

Cell Recognition and Counting

Automated quantification

Reduces manual intervention while keeping data consistent and accurate for easier experimental results

Intelligent Scan Path Planning

Intelligent Scan Path Planning

One image per minute

Automatically identifies ROIs and plans scan paths. A brain slice scan takes less than 1 minute; with a 10X objective and DAPI & GFP dual channels, a single brain slice takes only 40 seconds

High-precision Autofocus

High-precision Autofocus

Thick-slice surface imaging

Precisely focuses on the surface of thick brain slices, quickly captures clear images of key regions, and keeps focal planes consistent across all channels

One-click Brain Atlas Registration

Standard atlas comparison for efficient exploration of the brain

Rat Brain Atlas

Rat Brain Atlas

Mouse Brain Atlas

Mouse Brain Atlas

Macaque Brain Atlas

Macaque Brain Atlas

Ferret Brain Atlas

Ferret Brain Atlas

One-click automatic atlas registration, free from tedious work

One-click automatic atlas registration, free from tedious work

More complete slice registration with fewer worries

Tilted Brain Slice

Tilted Brain Slice

Damaged Brain Slice

Damaged Brain Slice

Half Brain Slice

Half Brain Slice

Precise positioning with a reliable manual reference

Side-by-side Standard 2D Atlas

Side-by-side Standard 2D Atlas

Bregma Positioning

Bregma Positioning

Automated Fluorescence Quantitative Analysis

Automatic Recognition and Statistics

Automatic Recognition and Statistics

Supports automatic recognition of DAPI, c-Fos, neurons, glial cells, and other signals, with statistics for positive signal count, area, and fluorescence intensity

Personalized Statistical Region Selection

Personalized Statistical Region Selection

Supports whole-brain, left-right brain, and custom brain-region statistics to meet diverse counting needs

Hierarchical Counting Statistics

Hierarchical Counting Statistics

Excel presents counting results by level, connecting upper and lower brain-region data clearly so complex brain-area statistics are easy to understand

High-performance Slice Scanner

One Image per Minute

One Image per Minute

Automatically identifies ROIs and plans scan paths, keeping each brain slice scan under 1 minute

99% Uniformity

99% Uniformity

Uniform illumination combined with global fluorescence background correction achieves up to 99% fluorescence background uniformity for high-quality multi-channel fluorescence images

No Channel Crosstalk

No Channel Crosstalk

Universal fluorescence channel configurations cover common fluorescence imaging applications, with customizable narrow-band excitation and emission filters to eliminate crosstalk anxiety

Low Phototoxicity

Low Phototoxicity

Strobe illumination provides millisecond-level high instantaneous power only during camera exposure, reducing phototoxic effects caused by continuous illumination

Simplified Far Beyond the Basics

Side LED Illumination

Side LED scattering illumination creates high-contrast fluorescent sample presentation without manual marker-pen sample positioning

Progress Indicator Light

An embedded ring light shows scan status and progress through color and completion state, making experiment progress easy to track

Parameter Templates

Scan parameters, image contrast, analysis regions, and export size settings can be saved as templates for fast reuse

Batch Export

Multi-channel fluorescence slice images support single-channel pseudo-color or grayscale export, multi-channel overlay export, and multi-marker batch export

Bring PanoBrain Into Your Lab

Move brain slice scanning, atlas registration, and quantitative analysis into a more efficient automated workflow

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